What is the genotype for a woman with hemophilia?
Expression and Transmission
What genotype causes hemophilia?
Hemophilia A and hemophilia B are inherited in an X-linked recessive pattern . The genes associated with these conditions are located on the X chromosome, which is one of the two sex chromosomes . In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition.
What is the probability that the couple will have a female with hemophilia?
Each daughter has a 1 in 2 (50%) chance of getting her mother’s hemophilia allele and being heterozygous. Overall, there is a 1 in 4 (25%) chance for each pregnancy that the baby will be a son with hemophilia and a 1 in 4 (25%) chance that the baby will be a heterozygous daughter.
Is hemophilia inherited from the mother or father?
The gene that causes hemophilia is passed from parent to child. A mother that carries the gene is called a carrier, and she has a 50% chance of having a son with hemophilia and a 50% chance of having a daughter who is also a carrier.
What is the genotype for females?
Genotypic sex refers specifically to an individual’s two sex chromosomes. Most people have either two X chromosomes (genotypic female) or an X and a Y chromosome (genotypic male).
What is the genotype of a female with hemophilia quizlet?
What are the genotypes of her mother and her father? A hemophiliac woman must be XhXh .
Is PP genotype or phenotype?
Predicting Offspring Phenotypes
Only offspring with the pp genotype will have the white-flower phenotype. Therefore, in this cross, you would expect three out of four (75 percent) of the offspring to have purple flowers and one out of four (25 percent) to have white flowers.
Is hemophilia A genotype or phenotype?
Haemophilia was previously regarded as a classical example of Mendelian inheritance, with mutation in only a single gene (F8 or F9) causing the disease phenotype. The disease manifests complete penetrance. Studies, however, revealed the striking genetic and phenotypic heterogeneities of the disease.
What chromosome is hemophilia on?
Hemophilia is caused by a mutation or change, in one of the genes, that provides instructions for making the clotting factor proteins needed to form a blood clot. This change or mutation can prevent the clotting protein from working properly or to be missing altogether. These genes are located on the X chromosome.
What is the probability of a normal woman who marries a man with hemophilia to have a hemophilic son and a hemophilic daughter?
a 25% (one in four) chance of having a son with hemophilia. a 25% chance of having a son with normal blood clotting. a 25% chance of having a daughter who is a carrier. a 25% chance of having a daughter who has hemophilia.
What is the genotype of the male?
When a sperm carrying the Y chromosome fertilizes an egg, the resulting embryo has a genotype of XY and will be a male. With rare exceptions, all other embryos will be XX or female. Although the Y chromosome codes for a male, the X chromosome is vital for normal human development.
What is the genotype of a male with hemophilia quizlet?
Since hemophilia is recessive (h), a female must have two copies of the recessive allele to have the disease. A human male (XY), on the other hand, has only one X chromosome, and so needs only one copy of the recessive allele to have the disease.
What is the genotype of a male with hemophilia?
When the offspring do not have a XH and only have the Xh allele/alleles they will have the hemophilia condition. Man’s genotype is XhY.
How do girls inherit hemophilia?
A females inherits one X chromosome from each parent. A male can have hemophilia if he inherits an affected X chromosome (an X chromosome with a mutation in the gene that causes hemophilia) from his mother.
How can a girl get hemophilia?
Hemophilia is a rare blood disease that usually occurs in males. In fact, it’s extremely rare for women to be born with the condition because of the way it’s passed down genetically. A female would need to inherit two copies of the faulty gene — one from each parent — to develop hemophilia A, B or C.