What is XYY chromosome disorder?

What does XYY syndrome cause?

47,XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Affected boys can have delayed development of motor skills (such as sitting and walking) or weak muscle tone (hypotonia).

Is XYY syndrome bad?

Most boys with XYY syndrome can grow up healthy, have normal sexual development and fertility, and lead productive lives. Symptoms can vary greatly among boys. Depending on which symptoms a boy has and how severe they are, doctors may recommend various treatments.

What is the life expectancy of someone with XYY syndrome?

The median age of survival was 77.9 years for controls and 67.5 years for 47,XYY persons, corresponding to a loss of median lifespan of 10.3 years.

What is the gender of XYY?

XYY syndrome is a genetic condition found in males only. About 1 in 1,000 boys have it. Boys with XYY syndrome — also known as 47,XYY — might be taller than other boys.

Can females have XYY syndrome?

Being male is the biggest risk factor. Most cases of XYY syndrome are not inherited, and the syndrome occurs randomly in pregnancies of women from all ages and ethnic backgrounds. People normally have 46 chromosomes in each cell.

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What is the treatment for XYY syndrome?

Treatment of XYY syndrome is symptomatic and supportive. Speech therapy, occupational therapy, or assistance for learning disabilities in the school setting may be of benefit.

Are XYY males infertile?

4 Discussion. Nonmosaic 47, XYY syndrome is an aneuploidy of sex chromosomes. It is often associated with male infertility. In our study the incidence rate was 0.1% (21/19,842) which is in accordance with a previously reported incidence rate.

Why would someone get tested for XYY syndrome?

47, XYY syndrome may be suspected when a doctor observes signs and symptoms that can be associated with the syndrome such as low muscle tone ( hypotonia ), speech delay, or learning problems in school. A doctor may then order testing to see if there is a genetic explanation for the signs and symptoms.

Why is it called Superman Syndrome?

The term ‘superman’ refers to the presence of the additional male-defining Y chromosome and affects approximately 1 in every 850 males.

What diseases are caused by an extra chromosome?

A trisomy is a chromosomal condition characterised by an additional chromosome. A person with a trisomy has 47 chromosomes instead of 46. Down syndrome, Edward syndrome and Patau syndrome are the most common forms of trisomy.

What percent of the population has Jacob’s syndrome?

It is estimated that only 15–20% of children with 47,XYY syndrome are ever diagnosed. Of these, approximately 30% are diagnosed prenatally. For the rest of those diagnosed after birth, around half are diagnosed during childhood or adolescence after developmental delays are observed.

Does having an extra Y chromosome make you a killer?

The court found that while an extra Y chromosome seems like a logical explanation for mutant-aggressive behaviour, there is not much evidence that links the X or Y chromosome to the deviant behaviour of serial killers.

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What are intersex chromosomes?

46, XY INTERSEX. The person has the chromosomes of a man, but the external genitals are incompletely formed, ambiguous, or clearly female. Internally, testes may be normal, malformed, or absent. This condition is also called 46, XY with undervirilization.